¡¾ÕªÒª¡¿Ä¿µÄ£º½¨Á¢×¢ÉäÓÃÑ×çúÄþϸ¾úÄÚ¶¾Ëؼì²é·½·¨¡£·½·¨£º°´¡¶ÖйúÒ©µä¡·2005Äê°æ(¶þ²¿)¸½Â¼ÊÕÔصÄϸ¾úÄÚ¶¾Ëؼì²é·½·¨¼°Ö¸µ¼ÔÔò½øÐÐʵÑé¡£½á¹û£º×¢ÉäÓÃÑ×çúÄþ¾1¡ú40±¶Ï¡Êͺó¶Ôö×ÊÔ¼ÁÎÞ¸ÉÈÅ×÷Ó᣽áÂÛ:ϸ¾úÄÚ¶¾Ëؼì²â·½·¨¿ÉÓÃÓÚ×¢ÉäÓÃÑ×çúÄþµÄÈÈÔ¼ì²é¡£
¡¾¹Ø¼ü´Ê¡¿Ï¸¾ú¶¾ËØö×ÊÔ¼ÁÑ×çúÄþHtPot10ºãνðÊôÔ¡
×¢ÉäÓÃÑ×çúÄþ¾ßÓÐÇåÈÈ¡¢½â¶¾¡¢¿¹Ñ׵ŦÄÜ£¬ÁÙ´²Ó¦ÓÃÓÚ²¡¶¾ÐÔ·ÎÑס¢²¡¶¾ÐÔÉϺôÎüµÀ¸ÐȾ¡£ÁÙ´²ÓÃÒ©¹ã·º£¬ÓÖ³£ÓÃÓÚ¾²ÂöµÎ×¢£¬ÏÖ±ê׼Ϊ½øÐÐÈÈÔ¼ì²é£Û£±£Ý£¬ÓÉÓÚϸ¾úÄÚ¶¾Ëؼì²é¾ßÓÐÁéÃô¶È¸ß£¬²Ù×÷¼ò±ã£¬ÖØÏÖÐԺõÄÓŵ㡣ÏÖ½«Ï¸¾úÄÚ¶¾ËØ·¨´úÌæÈÈÔ¼ì²é·¨¡£
1ÒÇÆ÷ÓëÊÔ¼Á
»ìÔÈÆ÷£»HtPot10ºãνðÊôÔ¡(ºÏ·Ê°¬±¾É¿ÆѧÒÇÆ÷ÓÐÏÞ¹«Ë¾)£»ÎÞÈÈÔÎüÍ·£¬Î¢Á¿ÒÆÒºÆ÷¡£
ϸ¾úÄÚ¶¾Ëع¤×÷Æ·(CSE£¬Ð§¼Û70EU/Ö§£¬ÅúºÅ2005?3£¬ÖйúÒ©Æ·ÉúÎïÖÆÆ·¼ì¶¨Ëù)£»ö×ÊÔ¼Á(TAL£¬ÁéÃô¶È0.125EU/ml£¬ÅúºÅ051109£¬050210£¬Õ¿½°²¶È˹ÉúÎïÓÐÏÞ¹«Ë¾)£»Ï¸¾úÄÚ¶¾Ëؼì²éÓÃË®(ÅúºÅ200050208£¬º¬Á¿¡Ü0.03EU/ml£¬Õ¿½º£ÑóÉúÎïÖÆÆ·¼ì¶¨³§)£»×¢ÉäÓÃÑ×çúÄþ(¹©ÊÔÆ·£¬¹æ¸ñÿ֧0.2g£¬ÅúºÅ051209¡¢0501018¡¢050926£¬¹þ¶û±õÈýÁªÒ©ÒµÓÐÏÞ¹«Ë¾)¡£
2·½·¨Óë½á¹û
2.1ö×ÊÔ¼ÁÁéÃô¶È(¦Ë)¸´ºË°´Ï¸¾úÄÚ¶¾Ëؼì²é·¨£Û£²£Ý£¬ÓÃBETË®½«Ï¸¾úÄÚ¶¾Ëع¤×÷±ê׼ƷϡÊͳÉ2¡¢1¡¢0.5¡¢0.25¦Ë4¸öŨ¶È½øÐÐʵÑé¡£½á¹û±íÃ÷£¬ÁéÃô¶ÈΪ0.125EU/mlµÄö×ÊÔ¼Á·ûºÏ¹æ¶¨¡£¼û±í1¡£½«±í1Êý¾Ý´úÈ빫ʽ¦Ëc=lg-1¡Æxini¦Ëc=0.125¡£±í1ö×ÊÔ¼ÁÁéÃô¶È¸´ºËʵÑé½á¹û£¨ÂÔ£©
2.2×¢ÉäÓÃÑ×çúÄþϸ¾úÄÚ¶¾ËØÏÞÖµ(L)µÄÈ·¶¨L=K/M£¬Ê½ÖÐKΪ¹æ¶¨µÄ¸øҩ;¾¶£¬ÈËÓÃÿǧ¿ËÌåÖØÿ1h¿É½ÓÊܵÄÄÚ¶¾ËØ×î´ó¼ÁÁ¿£¬×¢Éä¼ÁµÄK=5.0EU/kg¡¤h£»MΪÈËÓÃÿǧ¿ËÌåÖØÿ1h¸øÒ©µÄ×î´ó¼ÁÁ¿£¬¾¼ÆË㣬¹©ÊÔÆ·M=1.0ml/kg¡¤h£¬Òò´Ëϸ¾úÄÚ¶¾ËØÀíÂÛÏÞֵΪ£ºL=K/M=5/1.0=5EU/ml¡£
2.3¹©ÊÔÆ·µÄ×î´óÓÐЧϡÊͱ¶Êý(MVD)Ñ¡ÓÃÁéÃô¶ÈΪ0.125EU/mlö×ÊÔ¼Áʱ£¬MVD=L¦Ëb=50.125=40±¶¡£
2.4¹©ÊÔÆ·¸ÉÈųõɸÊÔÑéÓÃBETË®½«×¢ÉäÓÃÑ×çúÄþ(ÅúºÅ051209)·Ö±ðÏ¡ÊͳÉÔÒº¡¢1¡ú10¡¢1¡ú20¡¢1¡ú40ϵÁÐŨ¶È£¬ÒÔ¸÷Ï¡ÊÍŨ¶È¹©ÊÔÆ·½«Ï¸¾úÄÚ¶¾Ëع¤×÷±ê׼ƷϡÊͳÉ2¡¢1¡¢0.5¡¢0.25¦Ëb4¸öŨ¶ÈµÄÄÚ¶¾ËØÈÜÒº£¬Óëö×ÊÔ¼Á»ìºÏ½øÐÐÒÖÖÆ/ÔöÇ¿ÊÔÑ飬½á¹û±íÃ÷£¬¹©ÊÔÆ·ÔڽϸßŨ¶Èʱ¶Ôö×ÊÔ¼ÁÓиÉÈÅ×÷Óã¬Ö®Í⣬ÆäÖ±½Ó¶¾ÐÔ×÷Óÿɴ̼¤ÐÄѪ¹Ü¡¢¸ÎÔàµÈÔàÆ÷Ó빦ÄÜ£¬Êǵ¼Ö¸Îϸ°û¾ÖÔî»òÃÖÂþÐÔ»µËÀµÄÖ÷ÒªÔÒò¡£¸Îϸ°û¿É³öÏÖ¾ÖÔî»òÃÖÂþÐÔ»µËÀ£¬ÃÅÂöÖÜΧÏËά»¯¡£ÔÚ¹©ÊÔÆ·ÖÁÉÙ1¡ú40Ï¡ÊͺóÔò¶Ôö×ÊÔ¼ÁÎÞ¸ÉÈÅ×÷Óã¬
3С½á
×¢ÉäÓÃÑ×çúÄþΪÖÐÒ©×¢ÉäÒº£¬Îª´ó·Ö×ÓÎïÖÊ¡£ÔÚÔ¤ÊÔÑéÖУ¬¹©ÊÔÆ·µÄÔÒº¡¢1-10¡¢1-20Ï¡ÊÍÒº¶Ô±êʾÁéÃô¶ÈΪ0.5EU/mlºÍ0.25EU/mlµÄö×ÊÔ¼ÁÓÐÒÖÖÆ×÷Ó㬹ÊÑ¡Ôñ±êʾÁéÃô¶ÈΪ0.125EU/ml»òÁéÃô¶È¸üСµÄö×ÊÔ¼Á¡£Óɱ¾ÊÔÑé¿ÉÖª£¬Ö»Ð轫¹©ÊÔÆ·ÖÁÉÙ1-40Ï¡ÊÍ£¬¶Ôö×ÊÔ¼ÁµÄÒÖÖÆ×÷Óü´Ïûʧ¡£
²»Í¬ö×ÊÔ¼Á¶Ô¹©ÊÔÆ·µÄ·´Ó¦ÓвîÒì¡£±¾ÊµÑé²ÉÓÃÁ½ÖÖ²»Í¬ñ±ºÃµÄö×ÊÔ¼Áͬʱ½øÐÐÊÔÑ飬µÃµ½Á˽ÏΪÂúÒâ½á¹û¡£
±¾ÊÔÑé½á¹û֤ʵ£¬Ï¸¾úÄÚ¶¾Ëؼì²é·¨¿ÉÌæ´ú×¢ÉäÓÃÑ×çúÄþµÄÈÈÔ´¼ì²é£¬¼ì²éʱֻҪ½«ÖÁÉÙ1-40Ï¡ÊÍ£¬Ñ¡ÔñÏàÓ¦ÁéÃô¶ÈµÄö×ÊÔ¼Á¼´¿É½øÐС£
ÉÏһƪ£ºßÁ¿©À࿹Õæ¾úÒ©ÎïÖƼÁ΢ÉúÎïÏ޶ȼì²é·½·¨µÄÑо¿
ÏÂһƪ£ºÎÞ¾ú¼ì²é·¨-2015°æÖйúÒ©µä